Comparisons of mutation rate variation at genome-wide microsatellites: evolutionary insights from two cultivated rice and their wild relatives |
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Authors: | Li-zhi Gao Hongyan Xu |
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Affiliation: | (1) Plant Germplasm and Genomics Center, Kunming Institute of Botany, The Chinese Academy of Sciences, 650204 Kunming, P. R. China;(2) Department of Biostatistics, Medical College of Georgia, 1120 15th St., 30912 Augusta, GA, USA |
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Abstract: | Background Mutation rate (μ) per generation per locus is an important parameter in the models of population genetics. Studies on mutation rate and its variation are of significance to elucidate the extent and distribution of genetic variation, further infer evolutionary relationships among closely related species, and deeply understand genetic variation of genomes. However, patterns of rate variation of microsatellite loci are still poorly understood in plant species. Furthermore, how their mutation rates vary in di-, tri-, and tetra-nucleotide repeats within the species is largely uninvestigated across related plant genomes. |
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