Spontaneous tubular (cuboidal) metaplasia of the parietal layer of Bowman's capsule in Cynomolgus monkeys (Macaca fascicularis) |
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| Authors: | J Kaspareit S Friderichs-Gromoll E Buse G Habermann |
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| Affiliation: | Covance Laboratories, Department of Pathology, Kesselfeld 29, Münster 48163, Germany |
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| Abstract: | Tubular (cuboidal) metaplasia of the parietal epithelium of Bowman's capsule was observed in 19 (10 males, 9 females) of 56 adult control Cynomolgus monkeys. Cuboidal epithelium replaced the normally present flattened epithelium to various degrees in animals affected. Cuboidal cells revealed an eosinophilic cytoplasm and vesicular nuclei, thus resembling proximal convoluted epithelial cells in all respects. Continuity of the cuboidal glomerular epithelium with that of the proximal tubule was occasionally observed. |
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| Keywords: | Bowman's capsule Glomerulum Parietal layer Cuboidal metaplasia Tubular metaplasia Primate Cynomolgus monkey |
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