Protection against electrophile and oxidative stress by induction of phase 2 genes: the quest for the elusive sensor that responds to inducers期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Protection against electrophile and oxidative stress by induction of phase 2 genes: the quest for the elusive sensor that responds to inducers

Authors:	WDavid Holtzclaw

Institution:	The Lewis B. and Dorothy Cullman Cancer Chemoprotection Center, Department of Pharmacology and Molecular Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA

Abstract:

Keywords:	AHH aryl hydrocarbon hydroxylase Ah receptor aryl hydrocarbon receptor ARE (EpRE) antioxidant (electrophile) response element BHA 2(3)-tert-butyl-4-hydroxyanisole t-BHQ tert-butylhydroquinone BHT 3 5-di-tert-butyl-4-hydroxytoluene BP benzo(a)pyrene Dex-mes dexamethasone 21-mesylate DMBA dimethylbenz(a)anthracene GST glutathione S-transferase (EC 2 5 1 18) Keap1 kelch-like ECH-associated protein 1 MARE Maf recognition element β-NF β-naphthoflavone NQO1 NAD(P)H:quinone oxidoreductase (also known as quinone reductase DT diaphorase menadione reductase EC 1 6 99 2) Nrf2 NF-E2-related factor 2 PAH polycyclic aromatic hydrocarbons TCDD dioxin 2 3 7 8-tetrachlorodibenzo-p-dioxin TPA 12-O-tetradecanoylphorbol 13-acetate TRE TPA response element XRE xenobiotic response element
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