Synthesis of 2'-amino-LNA purine nucleosides |
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Authors: | Ravn Jacob Rosenbohm Christoph Christensen Signe M Koch Troels |
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Affiliation: | Santaris Pharma A/S, H?rsholm, Denmark. jra@santaris.com |
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Abstract: | The first reported synthesis of 2'-amino-LNA purine nucleosides via a transnucleosidation is accomplished enabling the preparation of oligonucleotides incorporating 2'-amino-LNA with all four natural bases. |
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