Isolation and expression of a gene (CGR1) regulated during the yeast-hyphal transition in Candida albicans |
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| Authors: | Cho T Sudoh M Tanaka T Nakashima Y Chibana H Kaminishi H |
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| Institution: | Department of Oral Microbiology, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan. chot1@college.fdcnet.ac.jp |
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| Abstract: | We used RNA fingerprinting of arbitrarily primed PCR to isolate genes upregulated during the yeast-hyphal transition in Candida albicans. The sequence and expression of one of these genes (CGR1, Candida growth regulation) are presented. Our results suggest that CGR1 expression is associated with a growth cessation of yeast cells, a prerequisite for germination in this organism. |
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