In vitro properties of various growth factors and in vivo effects |
| |
Authors: | J Courty Y Courtois D Barritault |
| |
Institution: | 1. Inserm U 118, CNRS ERA 842, 29 rue Wilhem, 75016 Paris France.;1. Egalement de l''Université de Paris Val-de-Marne, Paris France. |
| |
Abstract: | This article summarizes some of the data that have been accumulated on several growth factors. Biochemical and biological properties of the Epidermal, Fibroblast, Astrocytes and Tumor growth factors (EGF, FGF, AGF, TGF) and those of growth factors derived from Platelets (PDGF), Brain (BDGF, ECGF), Eye (EDGF) and Cartilage (CDGF) are reviewed, as well as the in vitro mechanism of action of EGF and PDGF. The in vivo effects of these growth factors, particularly the experiments achieved to understand the physiological or physiopathological significance are described. The potential interest of these molecules in pharmacology and their use as wound healing agents is discussed. |
| |
Keywords: | revue facteurs de croissance agents cicatrisants review growth factors wound healing agents |
本文献已被 ScienceDirect 等数据库收录! |
|