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| 利用核磁共振同时观测大鼠心室内压参数与能量代谢 | |
| 作者姓名： | Cheng ZJ Du ZH Li HX Dong HJ Feng R Li GY |
| 作者单位： | 1. 解放军总医院微量元素研究室 2. 军事医学科学院国家生物医学分析中心,北京,100850 3. 山东省立医院心外科,济南,250021 4. 军事医学科学院毒物药物研究所,北京100850 |
| 基金项目： | “九五”军队卫生科研基金!资助项目 (No 96M0 4 2 ) |
| 摘 要： | 本文介绍一种在核磁共振（ｎｕｃｌｅａｒ ｍａｇｎｅｔｉｃ ｒｅｓｏｎａｎｃｅ,ＮＭＲ）谱仪上对大鼠主室内压参数与能量代谢同时测定的技术。该方法采用离体等容大鼠心功能监测系统测量和分析心脏的心室内压参数,通过测定心脏的磷－３１核磁共振（＾３１Ｐ ＮＭＲ）谱观测心肌组织的能量代谢状态。 |
| 关 键 词： | 核磁共振 离体心脏 能量代谢 心室内压 计算机 |
Simultaneous observation of parameter of intraventricular pressure and energy metabolism in rat hearts using nuclear magnetic resonance |
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| Cheng ZJ,Du ZH,Li HX,Dong HJ,Feng R,Li GY.Simultaneous observation of parameter of intraventricular pressure and energy metabolism in rat hearts using nuclear magnetic resonance[J].Acta Physiologica Sinica,1999,0(6):700-704. | |
| Authors: | Cheng Z J Du Z H Li H X Dong H J Feng R Li G Y |
| Institution: | National Center for Biomedical Analysis, Academy of Military Medical Science, Beijing 100850. |
| Abstract: | A technique for simultaneous observation of parameters of intraventricular pressure and energy metabolic status in isovolumic rat hearts was described. The parameters of intraventricular pressure were collected and processed using a computerized monitoring system for heart function, and myocardial energy metabolism was investigated by collecting the ~ 31 P NMR spectra. The preparation was stable metabolically and functionally for 2 h under the NMR experimental conditions. |
| Keywords: | NMR isolated heart energy metabolism |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |