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Etiology and microbiological diagnosis of nosocomial pneumonia in newborns]
Authors:G B Fadeeva  G V Sterkhova  S V Sidorenko  N N Volodin  M S Efimov  A B Dulenkov  N B Veselova  S A Mal'tseva  M G Suvorova
Affiliation:Municipal Clinical Hospital No 7, National Research Centre of Antibiotics, Faculty of Medical Training, Russian State Medical University, Russian Academy of Postgraduate Medical Training, Moscow.
Abstract:A comparative analysis of the cases of ventilator-associated pneumonia (VAP) among premature infants in intensive care units and premature infant nurseries in 1994 (group I) and 1999 (group II) is presented. It was shown that the number of the cases of ventilator-associated pneumonia in the premature infants of group. I was 2,4 times higher than that in the group II (45.8 and 19.2 per cent respectively). A marked difference in the species pattern of the pathogens isolated from the endobronchial aspirate in 1994 and 1999 was observed. The species pattern of the isolates from the respiratory tract (Pseudomonas aeruginosa--40 per cent; Klebsiella pneumoniae--31 per cent; Staphylococcus epidermidis and Enterococcus--rare) showed that the pneumonia were nosocomial. The revealed similarity of the species patterns of the microflora in various parts of the respiratory tract and the throat posterior wall made it possible to consider the isolates of the throat posterior wall as a relative guide for confirming the etiological diagnosis of nosocomial pneumonia.
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