Formation of a new 5'-guanylic acid helix in neutral solution |
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Authors: | H T Miles J Frazier |
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Affiliation: | National Institute of Arthritis, Metabolism and Digestive Diseases National Institutes of Health Bethesda, Maryland 20014 USA |
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Abstract: | 5′-GMP forms in neutral solution a regular, ordered structure, presumably helical. The ordered structure is different from that previously reported at pH 5 and is not associated with gel formation. The transition is more cooperative than that of the pH 5 helix, but has a lower Tm. |
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