| 南海链霉菌SCSIO 1635中抗霉素类化合物的分离鉴定(英文) |
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| 引用本文： | 李苏梅,田新朋,牛四文,张文军,张偲,鞠建华,张长生.南海链霉菌SCSIO 1635中抗霉素类化合物的分离鉴定(英文)[J].天然产物研究与开发,2011,23(1):10-14,42. |
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| 作者姓名： | 李苏梅 田新朋 牛四文 张文军 张偲 鞠建华 张长生 |
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| 作者单位： | 中国科学院南海海洋研究所海洋生物资源可持续利用重点实验室,海洋微生物研究中心广东省海洋药物重点实验室,广州,510301 |
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| 基金项目： | supported by the Funds of the Chinese Academy of Sciences for Key Topics in Innovation Engineering(KZCX2-YW-216,KSCX2-YW-G-065,KSCX2-YW-G-073); Natural Science Funds of South China Sea Institute of Oceanology for Young Scholar(SQ200903); Funds of Frontier Areas of SCSIO (LYQY200805); Open Project Program of Key Laboratory of Marine Bio-resources Sustainable Utilization(LMB091013) |
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| 摘 要： | 我们从南海海底沉积环境分离了一株放线菌SCSIO1635,经16S rDNA的序列分析将该株菌鉴定为链霉菌属。我们从该菌的发酵液中分离得到了4个化合物,经质谱和核磁共振波谱解析,确定为抗霉素类化合物:异构体antimycin A1a和A1b(1)、deisovalerylblastmycin(2)、kitamycin A(3)和antimycin A9(4)。
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| 关 键 词： | 南海沉积环境 海洋放线菌 海洋微生物天然产物 链霉菌 抗霉素 |
Antimycins from Marine Streptomyces sp.SCSIO 1635 from the South China Sea |
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| LI Su-mei,TIAN Xin-peng,NIU Si-wen,ZHANG Wen-jun,ZHANG Si,JU Jian-hua,ZHANG Chang-sheng.Antimycins from Marine Streptomyces sp.SCSIO 1635 from the South China Sea[J].Natural Product Research and Development,2011,23(1):10-14,42. |
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| Authors: | LI Su-mei TIAN Xin-peng NIU Si-wen ZHANG Wen-jun ZHANG Si JU Jian-hua ZHANG Chang-sheng |
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| Institution: | LI Su-mei,TIAN Xin-peng,NIU Si-wen,ZHANG Wen-jun,ZHANG Si,JU Jian-hua,ZHANG Chang-sheng CAS Key Laboratory of Marine Bio-resources Sustainable Utilization,RNAM Center for Marine Microbiology,CAS,Guangdong Key Laboratory of Marine Materia Medica,South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou 510301,China |
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| Abstract: | The strain SCSIO 1635 was isolated from marine sediment of the South China Sea,and identified as a member of Streptomyces according to the 16S rDNA sequence.Four compounds were isolated from Streptomyces sp.SCSIO 1635.The compounds were found to be structurally-related to antimycins by detailed analyses of MS and NMR spectroscopic data,and were identified as antimycin A1a and A1b(1),deisovalerylblastmycin(2),kitamycin A(3),and antimycin A9(4),respectively. |
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| Keywords: | marine sediments of South China Sea marine actinomycetes marine microbial natural products Streptomyces antimycins |
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