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Transformation of 2-aminoacetophenone to (S)-2-amino-1-phenylethanol by Arthrobacter sulfureus
Authors:Guogang Zhao  Jianjun Wang  Kai Ma  Liu Yang  Sheng Wu  Yanbin Liu  Wanru Sun
Affiliation:State Key Laboratory of Microorganism Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, PR China.
Abstract:A new isolate of Arthrobacter sulfureus , when incubated at 50 g resting cells (dry cell wt) l(-1) with 50 g glucose l(-1) and 1 g 2-aminoacetophenone l(-1) in 50 mm potassium buffer (pH 7, 4 ml) at 30 degrees C, produced ( S )-2-amino-1-phenylethanol (e.e. >99%) with 75% yield in 6 h.
Keywords:2-amino-1-phenylethanol  Arthrobacter sulfureus  reduction
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