Transformation of 2-aminoacetophenone to (S)-2-amino-1-phenylethanol by Arthrobacter sulfureus |
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Authors: | Guogang Zhao Jianjun Wang Kai Ma Liu Yang Sheng Wu Yanbin Liu Wanru Sun |
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Affiliation: | State Key Laboratory of Microorganism Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, PR China. |
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Abstract: | A new isolate of Arthrobacter sulfureus , when incubated at 50 g resting cells (dry cell wt) l(-1) with 50 g glucose l(-1) and 1 g 2-aminoacetophenone l(-1) in 50 mm potassium buffer (pH 7, 4 ml) at 30 degrees C, produced ( S )-2-amino-1-phenylethanol (e.e. >99%) with 75% yield in 6 h. |
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Keywords: | 2-amino-1-phenylethanol Arthrobacter sulfureus reduction |
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