Blood cells contribute to glial repair in an insect |
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Authors: | Howes E A Chain B M Smith P J Treherne J E |
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Affiliation: | Zoology Department, University College, London WC1E 6BT, U.K. |
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Abstract: | Using antibodies specific for haemocytes, we have shown that these blood cells penetrate the abdominal nervous connectives of the cockroach following selective disruption of the glia using the DNA-intercalating drug, ethidium bromide, as a glial toxin. Within 4 days post-lesion, the labelled cells formed a mosaic beneath the neural lamella and penetrated deeply among the disrupted subperineurial glia. These observations confirm that exogenous cells are involved in glial repair and support a previous hypothesis that they play critical roles in both structural repair and the recruitment of endogenous reactive cells. |
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Keywords: | Haemocytes glial repair insect |
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