Folate synthesis: an old enzyme identified |
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Authors: | McLennan Alexander G |
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Institution: | 1. School of Biological Sciences, University of Liverpool, Liverpool L69 7ZB, United Kingdom |
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Abstract: | In this issue of Structure, Amzel, Bessman, and colleagues (Gabelli et al., 2007) present the crystal structure of a 17 kDa Nudix hydrolase from Escherichia coli previously characterized as a dATPase and provide evidence that it functions in vivo to remove pyrophosphate from the folate precursor dihydroneopterin triphosphate. |
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