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Association of two DNA polymorphisms in the alpha-globin gene cluster: implications for genetic analysis. |
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| Authors: | J S Wainscoat D R Higgs E Kanavakis A Cao D Georgiou J B Clegg D J Weatherall |
| Abstract: | A new polymorphic BgI II restriction endonuclease site in the alpha-globin gene complex has been found in Cypriot, Sardinian, and Greek populations. In all cases, this polymorphism is linked to a particular hypervariable region between the zeta 2 and zeta 1 genes. This suggests that these hypervariable regions are stable and will be useful for genetic analysis. |
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