Difference in polyamine transport in human B and T lymphocytes. |
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Authors: | S Colombatto B Fulgosi A Bianchi M Massaia M A Grillo |
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Affiliation: | Dipartimento di Medicina e Oncologia Sperimentale, Università di Torino. |
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Abstract: | Preparations enriched in human blood B lymphocytes are able to take up polyamines efficiently. Uptake by T cells is barely detectable. Human non-circulating B cells (from tonsils) have a much lower ability to take up polyamines, as do mixed populations of bovine lymph nodes. B cells contain a higher amount of endogenous polyamines and show higher ornithine decarboxylase activity than T cells. |
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