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| 畜禽疫苗佐剂研究进展 | |
| 引用本文： | 张玲华,郭勇,田兴山,潘木水,黄小光,周风珍,邝哲师,李国立,孙晓刚,陈薇. 畜禽疫苗佐剂研究进展[J]. 生物技术通讯, 2005, 16(2): 231-233 |
| 作者姓名： | 张玲华 郭勇 田兴山 潘木水 黄小光 周风珍 邝哲师 李国立 孙晓刚 陈薇 |
| 作者单位： | 1. 华南理工大学,生物工程学院,广东,广州,510641;广东省农业科学院,农业生物技术研究所,广东,广州,510640 2. 华南理工大学,生物工程学院,广东,广州,510641 3. 广东省农业科学院,农业生物技术研究所,广东,广州,510640 |
| 基金项目： | 广州市科技攻关重点项目(2003Z2-E0221)，广东省农业攻关项目(2003B21403) |
| 摘 要： | 畜禽用疫苗主要是亚单位疫苗、减毒或灭活细菌/病毒疫苗,为了使疫苗对动物能达到长效持久的保护,必须使用有效的佐剂.根据不同的作用方式,目前可将佐剂主要分为2大类:疫苗传递系统的佐剂、免疫刺激作用佐剂.本探讨了近年来畜禽用疫苗佐剂的功能及其发展趋势,概述了其应用研究的进展. |
| 关 键 词： | 畜禽疫苗佐剂 免疫刺激剂 疫苗传递系统 乳化 功能 发展趋势 |
| 文章编号： | 1009-0002(2005)02-0231-03 |
| 修稿时间： | 2004-06-16 |
Recent Progress in Veterinary Vaccine Adjuvant |
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| ZHANG Ling-hua,GUO Yong,Tian Xing-shan,Pan Mu-shui,HUANG Xiao-guang,ZHOU Feng-zhen,KUANG Zhe-shi,LI Guo-li,SUN Xiao-gang,CHEN Wei. Recent Progress in Veterinary Vaccine Adjuvant[J]. Letters in Biotechnology, 2005, 16(2): 231-233 | |
| Authors: | ZHANG Ling-hua GUO Yong Tian Xing-shan Pan Mu-shui HUANG Xiao-guang ZHOU Feng-zhen KUANG Zhe-shi LI Guo-li SUN Xiao-gang CHEN Wei |
| Affiliation: | ZHANG Ling-hua1,2,GUO Yong1,TIAN Xing-shan2,PAN Mu-shui2,HUANG Xiao-guang2,ZHOU Feng-zhen2,KUANG Zhe-shi2,LI Guo-li2,SUN Xiao-gang2,CHEN Wei21. Biological Engineering Institute,South China University of Technology,Guangzhou 510640,2. Bio-Tech Research Institute,Guangdong Academy of Agricultural Sciences. Guangzhou 510640,China |
| Abstract: | The veterinary vaccine mainly comprise of either subunit, live attenuated or inactivater bacteria/viruses. These vaccines would require optimal adjuvants and delivery systems to accord long-term protection from infectious diseases in animals. Adjuvants can be broadly divided into two classes, based on their principal mechanisms of action:vaccine delivery systems and immunostimulatory adjuvants. The function and development of adjuvant in animals were dicussed here, and the recent progress in application was also included. |
| Keywords: | veterinary vaccine adjuvants immunostimulator vaccine delivery systems emulsion |
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