Analysis of the features and source gene composition of the AluYg6 subfamily of human retrotransposons |
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Authors: | Pamela Styles John FY Brookfield |
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Affiliation: | (1) Institute of Genetics, School of Biology, University of Nottingham, Queens Medical Centre, Nottingham, UK |
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Abstract: | Background Alu elements are a family of SINE retrotransposons in primates. They are classified into subfamilies according to specific diagnostic mutations from the general Alu consensus. It is now believed that there may be several retrotranspositionally-competent source genes within an Alu subfamily. To investigate the evolution of young Alu elements it is critical to have access to complete subfamilies, which, following the release of the final human genome assembly, can now be obtained using in silico methods. |
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