| Abstract: | Extracts of dog olfactory mucosa were subjected to affinitychromatography on columns having exposed methoxyphenyl groups.Elution with p-anisic acid displaced a protein component demonstrablewith polyacrylamide gel electrophoresis. This was present inlarger amount in extracts made with the detergent, sodium dodecylsulfate, than in detergent-free extracts, suggesting that ithad originated in some membranous structure. It was not seenin extracts of nearby respiratory epithelium. It is hypothesizedthat this includes a recognition molecule through which odorantssuch as anisole stimulate olfactory receptors. |
