Photocatalyzed Anaerobic Oxidation of Nicotinamide Coenzyme Dimers to NAD+ by Adriamycin |
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| Authors: | Vincenzo Carelli Antonio Casini Alessandro Finazzi-Agro Felice Liberatore Silvano Tortorella |
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| Affiliation: | a Institute of Pharmaceutical Chemistry and Toxicology, University of Rome “La Sapienza”, Rome, Italyb Department of Experimental Medicine and Biochemical Sciences, University of Rome “Tor Vergata”, Rome, Italy |
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| Abstract: | The nicotinamide adenine dinucleotide dimers (NAD)2 obtained by electrochemical reduction of NAD+ are oxidized by adriamycin in anaerobic photocatalyzed reaction yielding NAD+ and 7-deoxyadriamyci-none. Under the same conditions NADH is not oxidized. |
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| Keywords: | Photocatalysis NAD adriamycin |
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