Optimized nikkomycin production by fed-batch and continuous fermentation |
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Authors: | Traugott C Schüz Hans-Peter Fiedler Hans Zähner |
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Institution: | (1) Biologisches Institut, LB Mikrobiologie/Antibiotika, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany |
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Abstract: | We performed fed-batch and continuous fermentations to extend the time of maximal nikkomycin production by Streptomyces tendae Tü 901/S 2566. This was achieved by the fed-batch culture technique. Furthermore, high productivity was obtained at slow growth rates in a continuous fermentation process. Different dilution rates with and without carbon limitation were done and the results were compared.
Correspondence to : T. Schüz |
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