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SeqTrim: a high-throughput pipeline for pre-processing any type of sequence read |
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| Authors: | Juan Falgueras Antonio J Lara Noé Fernández-Pozo Francisco R Cantón Guillermo Pérez-Trabado M Gonzalo Claros |
| Institution: | 1.Departamento de Lenguajes y Ciencias de la Computación,Universidad de Málaga,Málaga,Spain;2.Plataforma Andaluza de Bioinformática,Universidad de Málaga,Málaga,Spain;3.Departamento de Biología Molecular y Bioquímica,Universidad de Málaga,Málaga,Spain;4.Departamento de Arquitectura de Computadores,Universidad de Málaga,Málaga,Spain |
| Abstract: | BackgroundHigh-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to avoid database contamination with artefactual sequences. The arrival of pyrosequencing enhances this problem and necessitates customisable pre-processing algorithms. |
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