Synthesis,structure and a fourier transform infrared study of Pt(II), Cu(II), and Mg(II) Complexes with xanthosine-5′-monophosphate

The reaction of xanthosine-5′'-monophosphate disodium salt (5′-XMPNa₂) with Pt(II), Cu(II) and Mg(II) ions produced compounds of the type cis- and trans-Pt(NH₃)₂(XMPNa₂)_nCl₂·xH₂O, where n = 1 or 2; Pt(XMPNa₂)_nCl₂·xH₂O, where n = 1-4, x = 1,4 & 6; Cu(XMP)·6H₂O and Mg(XMP)·xH₂O, where x = 9 or 4. In the complexes synthesized here at neutral pH values, the nucleotide binds through the N_7-atom of the purine ring system, whereas for Cu(II) and Mg(II) compounds obtained at pH = 4 a direct metal-phosphate interaction as well as N_τ bonding is proposed.