The absence of 2,3-diphosphoglycerate from myocytes,hepatocytes and adipocytes |
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| Authors: | Williams J. Reddy Alastair H. Burns |
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| Affiliation: | Division of Endocrinology and Metabolism, Department of Medicine, University of Alabama School of Medicine, Birmingham, Ala. 35294, U.S.A. |
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| Abstract: | Myocytes, hepatocytes and adipocytes were prepared from heart, liver and epididymal fat pad of the rat. No detectable level of 2,3-diphosphoglycerate was found. Evidence is also present which indicates the absence from these cells of 2,3-diphosphoglycerate mutase and 2,3-diphosphoglycerate phosphatase. Previous findings by others of the presence of 2,3-diphosphoglycerate and 2,3-diphosphoglycerate mutase probably resulted from erythrocytes sequestered in the tissue. |
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