Bayesian shared spatial‐component models to combine and borrow strength across sparse disease surveillance sources |
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Authors: | Juan J. Abellan Víctor J. Del Rio Vilas Colin Birch Sylvia Richardson |
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Affiliation: | 1. Centre for Public Health Research (CSISP), , 46020 Valencia, Spain;2. CIBER Epidemiología y Salud Pública (CIBERESP), , Spain;3. Department of Food Environment and Rural Affairs (Defra), , London, SW1P 3JR UK;4. Veterinary Laboratories Agency, , Addlestone, Surrey, KT15 3NB UK;5. Department of Epidemiology and Public Health, Imperial College London, , London, W2 1PG UK |
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Abstract: | When analyzing the geographical variations of disease risk, one common problem is data sparseness. In such a setting, we investigate the possibility of using Bayesian shared spatial component models to strengthen inference and correct for any spatially structured sources of bias, when distinct data sources on one or more related diseases are available. Specifically, we apply our models to analyze the spatial variation of risk of two forms of scrapie infection affecting sheep in Wales (UK) using three surveillance sources on each disease. We first model each disease separately from the combined data sources and then extend our approach to jointly analyze diseases and data sources. We assess the predictive performances of several nested joint models through pseudo cross‐validatory predictive model checks. |
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Keywords: | Bayesian statistics Data sparseness Gaussian Markov random fields Pseudo cross‐validatory predictive checks Spatial epidemiology |
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