| 含结构性倒位inv（5）（p13.1 q13.3）的毛细胞白血病细胞系的建立 |
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| 引用本文： | 李永青,朱传炳,吴秀山. 含结构性倒位inv（5）（p13.1 q13.3）的毛细胞白血病细胞系的建立[J]. 生命科学研究, 2001, 5(1): 39-41 |
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| 作者姓名： | 李永青 朱传炳 吴秀山 |
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| 作者单位： | 湖南师范大学 生命科学学院, |
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| 基金项目： | 湖南省特聘教授基金资助项目(25000613) |
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| 摘 要： | 为从分子水平揭示毛细胞白血病（HCL）的发病机理提供研究材料，将患者外周血淋巴细胞分离，用EBV病毒转化后进行细胞培养，建立细胞系，在连续传代3个月后，进行染色体组型分析，所培养细胞的染色体组型分析结果，与患者新鲜的外周血淋巴细胞的完全相同，证实该细胞系构建成功。
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| 关 键 词： | 毛细胞白血病 细胞系 染色体结构性倒位 建系 |
| 文章编号： | 1007-7847（2001）01-0039-03 |
| 修稿时间： | 2000-10-11 |
Establishment of the CellLine with a Constitutional Chromosomal |
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| LI Yong-qing,ZHU Chuan-bing,WU Xiu-shan. Establishment of the CellLine with a Constitutional Chromosomal[J]. Life Science Research, 2001, 5(1): 39-41 |
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| Authors: | LI Yong-qing ZHU Chuan-bing WU Xiu-shan |
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| Abstract: | To obtain material for the study of molecular phathological mechanism of hairy cell leukemia (HCL), lymphocyte cells were separated from peripheral blood from a patient with HCL and transformed with EBV. After the cell line was bequeathed for more than three months, karyotype analysis was performed. The same karyotype of the cell line as that of the patient with HCL was observed. Thus the cell line was successfully established. |
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| Keywords: | hairy cell leukemia (HCL) cell line constitutional chromosomal inversion |
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