Significant rate accelerated synthesis of glycosyl azides and glycosyl 1,2,3-triazole conjugates |
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| Authors: | Rishi Kumar Prakas R. Maulik Anup Kumar Misra |
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| Affiliation: | (1) Molecular and Structural Biology, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, 226001, UP, India;(2) Medicinal and Process Chemistry Division, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, 226001, UP, India |
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| Abstract: | An efficient and significantly rapid access of a series of glycosyl azides and glycosyl 1,2,3-triazole conjugates is reported using modified one-pot reaction conditions. In both cases yields were excellent and single diastereomers were obtained.  Figure Rapid preparation of 4-substituted glycosyl 1,2,3-triazole conjugates from glycosyl bromides. CDRI communication no. 7340. |
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| Keywords: | Glycosyl azides Glycosyl triazoles Glycosyl bromides Click chemistry One-pot |
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