TAM: A method for enrichment and depletion analysis of a microRNA category in a list of microRNAs |
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Authors: | Ming Lu Bing Shi Juan Wang Qun Cao Qinghua Cui |
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Institution: | (1) Department of Biomedical Informatics, Peking University Health Science Center, Beijing, 100191, China;(2) Department of Cardiology, Beijing Military General Hospital, Beijing, 100700, China |
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Abstract: | Background MicroRNAs (miRNAs) are a class of important gene regulators. The number of identified miRNAs has been increasing dramatically
in recent years. An emerging major challenge is the interpretation of the genome-scale miRNA datasets, including those derived
from microarray and deep-sequencing. It is interesting and important to know the common rules or patterns behind a list of
miRNAs, (i.e. the deregulated miRNAs resulted from an experiment of miRNA microarray or deep-sequencing). |
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Keywords: | |
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