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Functional CT: physiological models
Institution:1. Section of Pediatric Cardiac Surgery, The Maria Fareri Children’s Hospital, Westchester Medical Center, Valhalla, New York;2. Section of Adult Cardiac Surgery, Westchester Medical Center, Valhalla, New York;3. Section of Vascular Surgery, Westchester Medical Center, Valhalla, New York;1. Department of Nuclear Medicine, Kuwait Cancer Control Center (KCCC), Khiatan, Kuwait;2. Department of Surgery, Kuwait Cancer Control Center (KCCC), Khiatan, Kuwait;3. Department of Pathology, Kuwait Cancer Control Center (KCCC), Khiatan, Kuwait;4. Jack Brignall PET/CT Centre, Castle Hill Hosptial, Cottingham, UK;1. Department of Radiology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China;2. Department of Interventional Radiology, No. 2 People’s Hospital of Changzhou, Nanjing Medical University, Changzhou, China;3. Department of Radiology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224;1. Molecular Ecology and Evolution Programme, Department of Genetics, University of Pretoria, Pretoria 0002, South Africa;2. Evolution of Interactions Group, Department of Genetics, University of Pretoria, Pretoria 0002, South Africa;1. Research Division, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand;2. Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand;3. Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand;4. Oxidation in Red Cell Disorders and Health Task Force, Department of Clinical Microscopy, Faculty of Allied Health Science, Chulalongkorn University, Bangkok, Thailand
Abstract:Since its introduction three decades ago, computed tomography (CT) has been regarded as an imaging technique that is good at providing structural information but poor at providing physiological (functional) data to help with diagnosis. For instance, although it can reveal an abnormal mass present in the lung or liver, it cannot always differentiate a benign mass from a malignant growth. The introduction of fast CT scanners in the past decade, together with the development of better analysis techniques, has helped to launch functional CT as a new method to investigate the physiological basis of function and disease in the human body.
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