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Cingulate cortex hypoperfusion predicts Alzheimer's disease in mild cognitive impairment

Authors:	Email author" target="_blank">Chaorui?Huang Email author Lars-Olof?Wahlund Leif?Svensson Bengt?Winblad Per?Julin

Institution:	(1) Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research (NEUROTEC), Divison of Geriatric Medicine, Karolinska Institutet, Huddinge University Hospital, StockHolm, Sweden;(2) Department of Hospital Physics, Karolinska Institutet, Huddinge University Hospital, StockHolm, Sweden

Abstract:	Background Mild cognitive impairment (MCI) was recently described as a heterogeneous group with a variety of clinical outcomes and high risk to develop Alzheimer's disease (AD). Regional cerebral blood flow (rCBF) as measured by single photon emission computed tomography (SPECT) was used to study the heterogeneity of MCI and to look for predictors of future development of AD.

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