Isolation of a natural cytotoxic IgM "antibody" in human serum sensitizing L cells to complement |
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| Authors: | R P Bolande D C Mayer |
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| Affiliation: | Department of Pathology, East Carolina University, School of Medicine, Greenville, North Carolina 27855. |
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| Abstract: | An IgM fraction of human serum was isolated and purified. A portion of this fraction firmly attaches to L cells' surfaces, which sensitizes these cells to the lytic action of low concentrations of serum C. It contains the natural cytotoxic "antibody" to L cells. |
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