New Bitter C27 and C30 Terpenoids from the Fungus Ganoderma lucidum (Reishi) |
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| Authors: | Tsuyoshi Nishitoba Hiroji Sato Takanori Kasai Hirokazu Kawagishi Sadao Sakamura |
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| Affiliation: | Department of Agricultural Chemistry, Faculty of Agriculture, Hokkaido University, Sapporo 060, Japan |
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| Abstract: | Four new bitter terpenoids, lucidenic acids A (1), B (2), C (3) and ganoderic acid C (5), were isolated from the fruiting bodies of Ganoderma lucidum, together with the known bitter ganoderic acid B (4). On the basis of spectroscopic data and chemical conversion, their structures were determined to be 7β-hydroxy-4,4,14α-trimethyl-3,11,15-trioxo-5α-chol-8-en-24-oic acid, 7β,12β-dihydroxy-4,4,14α-trimethyl-3,11,15-trioxo-5α-chol-8-en-24-oic acid, 3β,7β,12β-trihydroxy-4,4,14α-trimethyl-11,15-dioxo-5α-chol-8-en-24-oic acid and 7β-hydroxy-3,11,15,23-tetraoxo-5α-lanost- 8-en-26-oic acid, respectively. |
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