Synthesis and Biological Activity of Methyl 3-Demethyl-Abscisate and Its Related Analogs |
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| Authors: | Kyohei Yamashita Tomoko Watanabe Masashi Watanabe Takayuki Oritani |
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| Institution: | Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku University, Sendai 980, Japan |
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| Abstract: | To elucidate the role of the methyl substituent on the side chain of abscisic acid (ABA), we synthesized (2Z,4E)-3-demethyl-α-ionylideneacetic acid (4) and its related analogs, methyl (2Z)-3-demethyl-β-ionylideneacetate 1′,2′-epoxide (9) and methyl (2Z) and (2E)-3-demethyl-abscisate (12) and (13). The biological assay of these compounds suggested that the 3-methyl group on the side chain of ABA was indispensable to biological activity. |
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| Keywords: | xapA guaA xanthosine phosphorylase inosine production Escherichia coli |
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