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DNA Breaking Reaction with Catecholamines
Authors:Hiroki Murakami  Sanetaka Shirahata  Chikafumi Hori  Hideharu Yoshii  Koji Yamada  Kazuki Shinohara
Affiliation:Department of Food Science and Technology, Faculty of Agriculture, Kyushu University, Fukuoka
Abstract:Breaking activity of catecholamines and their structural analogues on λ DNA were investigated by agarose slab gel electrophoresis. Since λ DNA has a homogenous molecular size, it is a favorable material to detect the activity of DNA breaking reagent. Among the compounds tested, those having enediol group were only active, though their activities remarkably differed owing to their side chains. The profile of the breaking reaction was studied in detail by the use of one of the catecholamines, epinephrine.
Keywords:batatasin III  dihydrostilbene derivatives  GA3-dependent α-amylase induction  abscisic acid-like activity
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