N6-Alkylthiomethyl and N6-Arylthiomethyl Derivatives of Adenosine and Their Cytokinin Activity |
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Authors: | Yoshimitsu Yamazaki Hideo Suzuki Akira Kamibayashi Naoharu Watanabe Nobutaka Takahashi |
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Institution: | 1. Fermentation Research Institute, Yatabe-cho, Ibaraki 300-21;2. Department of Agricultural Chemistry, The University of Tokyo, Tokyo 113 |
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Abstract: | Five new derivatives of adenosine, N6-(1-methylethyl)thiomethyl]-(1), N6-methyithiomethyl-(2), N6-phenylthiomethyl-(3), N6-(3-amino-3-carboxypropyl)thiomethyl]-(4), and N6-(2-amino-2-carboxyethyl)thiomethyl]adenosine (5), were synthesized and their cytokinin activity was tested in the Amaranthus betacyanin assay and the soybean callus growth.1, 2, and 3 were active in the former assay and all five compounds were active in the latter assay. The activities of the compounds were, however, weaker than those of the reference derivatives, in which Sulfides were replaced by methylenes, N6-isopentyl-, N6-n-propyl-, N6-benzyl-, and N6-(5-amino-5-carboxypentyl)adenosine. This fact indicates that the sulfide structure introduced into the N6-side chains had the effect of reducing cytokinin activity. |
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Keywords: | Pseudomonas solvent tolerance fatty acid cell membrane |
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