Formation Mechanism of the Free Radical Product and Its Precursor by the Reaction of Dehydro-L-ascorbic Acid with Amino Acid |
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Authors: | Tateki Hayashi Mitsuo Namiki Keiichi Tsuji |
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Affiliation: | 1. Department of Food Science and Technology, Faculty of Agriculture, Nagoya University, Chikusa-ku Nagoya 464, Japan;2. The Institute of Physical and Chemical Research, Wakoshi Saitama 351, Japan |
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Abstract: | During the formation of radical A (2) and its precursor (tris(2-deoxy-2-L-ascorbyl)amine, 1) by the reaction of dehydroascorbic acid (DHA) with amino acid, ascorbic acid (AsA) and the reduced red pigment (3) were newly identified, in addition to scorbamic acid (SCA) and the red pigment (4), as intermediate products. The addition of AsA to the DHA-amino acid reaction, as well as to the DHA-SCA reaction, greatly increased the formation of 3 and 1. The reaction of AsA with 4 gave rapidly 3, followed by the gradual production of 1. From these results, a reaction pathway is proposed that 3 formed by the reduction of 4 with AsA is a key intermediate and its condensation with DHA followed by reduction with AsA might produce 2 and 1. |
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Keywords: | electrogenic Na+ absorption colon Na+, K+-ATPase cAMP |
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