Formation of Coenzyme Q11 by Pseudomonas M16, a Mutant |
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Authors: | Yohei Natori Tomohisa Nagasaki |
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Institution: | Central Research Laboratory, Nisshin Flour Milling Co., Ltd, Ohi, Iruma, Saitama, Japan |
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Abstract: | Pseudomonas M16 is the mutant derived from a facultative methylotroph, Pseudomonas N842, which is the potent producer of coenzyme Q10 (CoQ10). This mutant with elevated productivity of CoQ10 was observed to accumulate the significant amount of another CoQ homolog, which could not be detected in the parent strain. This CoQ homolog was extracted from the intact cells of the mutant and purified to crystaline state. The chemical properties and the results of UV, NMR and mass spectrometries revealed that this CoQ homolog was CoQ11. |
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Keywords: | α-mannosidase Shewanella amazonensis glycoside hydrolase family 99 N-glycosylation pyridylamino sugar |
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