Biosynthesis of Biotin-vitamers from Pelargonie Acid by Pseudomonas sp. Strain 393 |
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| Authors: | Masahiro Ohsugi Yasuko Inoue Masako Kuki Kikuko Imai Hiroko Deguchi |
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| Affiliation: | Laboratory of Applied Microbiology, Department of Food Science, Faculty of Home Economics, Mukogawa Women’s University, Nishinomiya 663, Japan |
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| Abstract: | The biosynthesis of biotin-vitamers from pelargonic acid by Pseudomonas sp. strain 393 was investigated. The main product of biotin-vitamers from pelargonic acid was desthiobiotin. The addition of streptomycin or l-alanine enhanced accumulation of desthiobiotin in culture fluid. Propionic, pimelic and azelaic acids were identified as main metabolites from pelargonic acid. When propionic acid was incubated with resting cells, pelargonic and azelaic acids were formed. The biosynthetic pathway of pelargonic acid to pimelic acid was also studied. |
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