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Tree House Explorer: A Novel Genome Browser for Phylogenomics
Authors:Andrew J Harris  Nicole M Foley  Tiffani L Williams  William J Murphy
Affiliation:Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, USA;Interdisciplinary Program in Genetics & Genomics, Texas A&M University, College Station, TX, USA;Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Abstract:Tree House Explorer (THEx) is a genome browser that integrates phylogenomic data and genomic annotations into a single interactive platform for combined analysis. THEx allows users to visualize genome-wide variation in evolutionary histories and genetic divergence on a chromosome-by-chromosome basis, with continuous sliding window comparisons to gene annotations, recombination rates, and other user-specified, highly customizable feature annotations. THEx provides a new platform for interactive phylogenomic data visualization to analyze and interpret the diverse evolutionary histories woven throughout genomes. Hosted on Conda, THEx integrates seamlessly into new or pre-existing workflows.
Keywords:bioinformatics   cats   genome browser   phylogenomics
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