Lymphocyte subpopulations in Lynch syndrome II: an immunocytochemical study on gastrointestinal biopsies. Preliminary report |
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Authors: | S Senatore G S Jotti D Liguori M Chetrì A Attolini G Cristofaro M Gabrielli |
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Institution: | Servizio di Anatomia Patologica, Ospedale A. Di Summa, Brindisi. |
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Abstract: | Gastrointestinal biopsies from 18 members of a family with Lynch Syndrome II were evaluated and immunocytochemical studies were made to characterize the phenotypic expression of the tissue's immune populations. The intestinal findings suggest polyclonal B-cell activation related to the T-helper distribution. Our evaluation provides no specific information so far on the management of patients with Lynch Syndrome II. |
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