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Na+/ K+-pump activity in photoreceptors of the blowfly Calliphora : a model analysis based on membrane potential measurements
Authors:U Gerster  D G Stavenga  W Backhaus
Institution:(1) Free University of Berlin, Theoretical and Experimental Biology, Department of Biology, Thielallee 63, D-14195 Berlin, Germany Tel.: +49–30/8383182, Fax: +49–30/8384323, e-mail: gerster@zedat.fu-berlin.de, DE;(2) University of Groningen, Department of Biophysics, Nijenborgh 4, NL-9747 AG Groningen, The Netherlands, NL
Abstract:Na+/K+-pump activity and intracellular Na+ and K+ concentration changes in blowfly photoreceptors are derived from intracellular potential measurements in␣vivo with a model based on the Goldman-Hodgkin-Katz theory for membrane currents. The relation between the intracellular Na+ concentration and the pump activity appears to follow a Hill function with a Hill coefficient of 1 and a maximal possible Na+ current due to pump activity of about −4 nA. The developed photoreceptor model incorporates the slow and fast voltage-dependent K+ channels of the blowfly photoreceptor of which the properties were taken from the literature. Accepted: 5 August 1996
Keywords:Sodium   pump       Photoreceptor       Afterhyperpolarization       Voltage-dependent   K+-channel       Blowfly  Calliphora
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