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Modulation of vigabatrin induced cerebellar injury: the role of caspase-3 and RIPK1/RIPK3-regulated cell death pathways
Authors:Abd El-kader  Marwa  Hamza  Eman  El-Gamal  Randa  Eladl  Amira Sobhy Rashed  El Nashar  Eman Mohamad  Alghamdi  Mansour A  Erfan  Omnia S
Institution:1.Department of Anatomy, Faculty of Medicine, Mansoura University, 35516, Mansoura, Egypt
;2.Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt
;3.Department of Pharmacology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
;4.Department of Histology and Cell Biology, Faculty of Medicine, Benha University, Banha, Egypt
;5.Department of Anatomy, College of Medicine, king Khalid University, Abha, Saudi Arabia
;6.Genomics and Personalized Medicine Unit, College of Medicine, King Khalid University, Abha, Saudi Arabia
;
Abstract:Journal of Molecular Histology - Vigabatrin is the drug of choice in resistant epilepsy and infantile spasms. Ataxia, tremors, and abnormal gait have been frequently reported following its use...
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