Production of proteoglycans by immobilized chondrocytes: Effect of divalent cations |
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| Authors: | Christian Tamponnet Maurice Lievremont |
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| Institution: | (1) Laboratoire Interdisciplinaire de Recherches en Biologie Appliquée, Ecole Normale Supérieure de Cachan, 61 avenue du Président Wilson, 94235 Cachan, France |
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| Abstract: | Summary Rabbit articular chondrocytes immobilized in alginate beads maintained normal morphology and metabolic activity (glucose consumption) for more than two weeks whether calcium, barium, or strontium were used for the gel forming. Only Ca- and Ba-alginate immobilized chondrocytes produced proteoglycans in the external medium. Only Ca-alginate beads produced proteoglycans at a constant rate. |
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