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Early and late replication patterns of increased resolution in human lymphocyte chromosomes |
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| Authors: | Barbara Meer H. Hameister Mabel Cerrillo |
| Affiliation: | (1) Institut für Humangenetik und Anthropologie, Albertstrae 11, D-7800 Freiburg, Federal Republic of Germany;(2) Present address: CH. 20 de Noviembre, Sección Genética, Laboratorio de Pruebas Especiales, Calle Roberto Gayol n ° 1419, Col. del Valle ZP 12, México D.F. |
| Abstract: | High resolution patterns of DNA replication in human lymphocyte chromosomes during early and late S-phases were studied by means of the BrdU-Hoechst-Giemsa technique. The late replicating bands were found to be identical with highly detailed G-bands. Between early replicating bands and R-bands subtile differences were observed. A possible correlation between a replication band seen on the chromosomal level and a replication cluster observed after fiber autoradiography is discussed. Dedicated to Professor Dr. Wolfgang Beermann on the occasion of his 60th birthday |
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