Estimation of the effects of chemical mutagens: Lessons from radiation genetics |
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| Authors: | Sheldon Wolff |
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| Affiliation: | 1. Laboratory of Radiobiology, University of California, San Francisco, California 94143, U.S.A.;2. >Department of Anatomy, University of California, San Francisco, California 94143, U.S.A. |
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| Abstract: | Years of work with ionizing radiations have given us a wealth of data on radiation-induced mutations. These data, which have given insights regarding the mutational processes, should form the background for all mutagenesis work. In chemical mutagenesis, as in radiation mutagenesis, it is important to know the shape of the dose-effect curve in order to make further interpretations and calculations. It is also important to be on the constant alert for new relations that can be explored. |
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| Keywords: | EMS ethyl methanesulfonate |
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