Sensitivity of the sodium efflux in barnacle muscle fibers to the microinjection of ATP |
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Authors: | E. Edward Bittar Edmund Tong |
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Affiliation: | Department of Physiology, University of Wisconsin Madison, Wisconsin 53706, U.S.A. |
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Abstract: | Sodium efflux in barnacle muscle fibers is promptly stimulated by internal application of ATP. This response is markedly augmented by pretreatment of the barnacle fiber with ouabain. ArP is found to be considerably less effective than ATP. It is suggested that the stimulatory response of the ouabain-insensitive Na efflux to the microinjection of ATP may be due to a significant rise in the sarcoplasmic cAMP concentration caused by the catalytic action of an adenyl cyclase system. |
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