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Steroidal constituents of Solanum xanthocarpum
Authors:Genjiro Kusano  Tsunematsu Takemoto  John A Beisler  Yoshio Sato
Institution:Pharmaceutical Institute, Tohoku University, Aobayama, Sendai, Japan;National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Services, U.S. Department of Health, Education and Welfare, Bethesda, MD, U.S.A.
Abstract:From the extract of the fruits of Solanum xanthocarpum (Solanaceae), five new steroidal compounds were isolated and characterized: 4α-methyl-24ξ-ethyl-5α-cholest-7-en-3β,22ξ-diol (1), 3β,22ξ-dihydroxy-4α-methyl-24ξ-ethyl-5α-cholest-7-en-6-one (2), 3β-benzoxy-14β,22ξ-dihydroxy-4α-methyl-24ξ-ethyl-5α-cholest-7-en-6-one (3), 3β-benzoxy-14α,22ξ-dihydroxy-4α-methyl-24ξ-ethyl-5α-cholest-7-en-6-one (4) and 3β-(p-hydroxy)-benzoxy-22ξ-hydroxy-4α-methyl-24ξ-ethyl-5α-cholest-7-en-6-one (5).
Keywords:Solanaceae  steroids  carpesterol derivatives  synthesis from carpesterol
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