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Investigations on drug produced and subjectively experienced discriminative stimuli: 1. The fentanyl cue,a tool to investigate subjectively experienced narcotic drug actions.
Authors:Francis C Colpaert  Harbans Lal  Carlos JE Niemegeers  Paul AJ Janssen
Institution:Department of Pharmacology Janssen Pharmaceutica, Research Laboratoria B-2340 Beerse, Belgium
Abstract:Fentanyl is reported to produce a discriminative stimulus that can control food-reinforced lever pressing in rats. Other narcotics (i.e. dextromoramide, morphine, phenoperidine and piritramide) are found to be generalized with fentanyl injection, whereas the neuroleptic haloperidol is not. The subjectively experienced narcotic cue is effectively controlled by the experimental procedures described.
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