Investigations on drug produced and subjectively experienced discriminative stimuli: 1. The fentanyl cue,a tool to investigate subjectively experienced narcotic drug actions. |
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Authors: | Francis C Colpaert Harbans Lal Carlos JE Niemegeers Paul AJ Janssen |
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Institution: | Department of Pharmacology Janssen Pharmaceutica, Research Laboratoria B-2340 Beerse, Belgium |
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Abstract: | Fentanyl is reported to produce a discriminative stimulus that can control food-reinforced lever pressing in rats. Other narcotics (i.e. dextromoramide, morphine, phenoperidine and piritramide) are found to be generalized with fentanyl injection, whereas the neuroleptic haloperidol is not. The subjectively experienced narcotic cue is effectively controlled by the experimental procedures described. |
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