Chemical constituents from the leaves of Crataegus pinnatifida Bge |
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| Affiliation: | 1. Baotou Medical College, Baotou, 014060, China;2. The First Affiliated Hospital of Baotou Medical College, Baotou, 014060, China;3. Guangxi Botanical Garden of Medicinal Plants, Nanning, 530023, China;4. Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot, 010020, China;1. School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Liaoning Province, Shenyang Pharmaceutical University, Shenyang, 110016, PR China;2. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, China;3. Chinese People′s Liberation Army 210 Hospital, Dalian, 116021, PR China;1. Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University College of Pharmacy, Yanji, PR China;2. Department of Pharmacy, Postdoctoral Research Station, Yanbian University Hospital, Yanji, PR China;3. Medical College, Inner Mongolia University for Nationalities, Tongliao, PR China |
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| Abstract: | The phytochemical investigations on the leaves of Crataegus pinnatifida led to the isolation of 20 compounds, including seven triterpenoids (1-7), three hydroxycinnamic acids (8-10), three lignans (11-13) and seven flavonoids (14-20). All chemical structures were established on the basis of NMR (1H NMR, 13C NMR) spectroscopic data. Meanwhile, compounds 3-12 are reported for the first time from Crataegus genus. In addition, compounds 10-11 are isolated from the family Rosaceae for the first time. On the basis of chemical research, the chemotaxonomic significance of the isolated compounds has been discussed. |
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| Keywords: | Rosaceae Crataegus pinnatifida Triterpenoids Flavonoids Chemotaxonomy |
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