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Chemical constituents from Scutellaria hainanensis C. Y. Wu
Institution:1. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, Hainan, 571158, PR China;2. Hainan Institute of Science and Technology, Haikou 571126, PR China;1. School of Pharmacy, Kumamoto University, 5-1 Oe-honmachi, Chuo ku, Kumamoto, 862-0973, Japan;2. Program for Leading Graduate Schools, Health Life Science: Interdisciplinary and Glocal Oriented (HIGO) Program, Kumamoto University, Kumamoto, Japan;1. School of Pharmacy, Nanchang University, 461 Bayi Road, Nanchang, Jiangxi, 330006, PR China;2. Center of Analysis and Testing, Nanchang University, Nanchang, 330047, PR China;3. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, PR China;1. Department of Chemistry, Higher Teacher Training College, University of Yaounde I, P. O. Box 47, Yaounde, Cameroon;2. Department of Animal Biology, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon;3. H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan;4. Pharmaceutical Research Center, PCSIR Laboratories Karachi Complex, Karachi, 75280, Pakistan;5. Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon;1. State Key Laboratory of Innovative Drugs and High Efficiency Energy Saving and Consumption Reduction Pharmaceutical Equipment, Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine, Key Laboratory of Modern Preparation of TCM of Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China;2. College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang, 473061, China;1. Key Laboratory of Marine Biogenetic Resources, South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen, 361005, China;2. Yanjing Medical College, Capital Medical University, 4 Dadong Road, Beijing, 101300, China
Abstract:Seventeen compounds were obtained from the extract of the whole plant of Scutellaria hainanensis C. Y. Wu. Including eleven flavonoids (1–4 and 7–13), two phenylpropanoids (16 and 17), one pyridinium derivative (5), one ester (6), one phenolic derivative (14), and one lignanoid (15). Compound 5 was a synthetic intermediate, newly identified as a natural product. The chemotaxonomic relationship between S. hainanensis C. Y. Wu and other species of genus Scutellaria were also discussed. As a result, the isolated glycoside compounds closely matched the ones obtained in other species of the genus.
Keywords:Scutellaria hainanensis C  Y  Wu  Flavonoids  Glycoside  Chemotaxonomy
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