Flavonoid glycosides from the leaves of Aphananthe aspera (Thunb.) Planch. (Cannabaceae) and their chemotaxonomic significance |
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| Institution: | 1. School of Pharmacy, Kumamoto University, 5-1 Oe-honmachi, Chuo ku, Kumamoto, 862-0973, Japan;2. Program for Leading Graduate Schools, Health Life Science: Interdisciplinary and Glocal Oriented (HIGO) Program, Kumamoto University, Kumamoto, Japan;1. Dipartimento di Biologia Ambientale, Piazzale Aldo Moro, 5, 00185, Rome, Italy;2. Dipartimento di Chimica: Università di Roma “La Sapienza”, Piazzale Aldo Moro, 5, 00185, Rome, Italy;3. Dipartimento di Scienze Farmaceutiche: Università degli Studi di Milano, Via Mangiagalli 25, I-20133, Milano, Italy;4. School of Pharmacy: University of Camerino, Via S. Agostino, 1 - 62032, Camerino, Italy;1. Université de Corse - CNRS, UMR 6134 SPE, Equipe Chimie et Biomasse, Route des Sanguinaires, 20000, Ajaccio, France;2. Neuchâtel Platform of Analytical Chemistry, University of Neuchâtel, Avenue de Bellevaux 51, 2000, Neuchâtel, Switzerland;1. Key Laboratory of Marine Biogenetic Resources, South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen, 361005, China;2. Yanjing Medical College, Capital Medical University, 4 Dadong Road, Beijing, 101300, China;1. CAS Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China;2. Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China;3. University of Chinese Academy of Sciences, Beijing, 100049, China;4. College of Marine Life Science, Ocean University of China, Qingdao, 266100, China;1. Department of Chemistry, Higher Teacher Training College, University of Yaounde I, P. O. Box 47, Yaounde, Cameroon;2. Department of Animal Biology, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon;3. H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan;4. Pharmaceutical Research Center, PCSIR Laboratories Karachi Complex, Karachi, 75280, Pakistan;5. Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon |
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| Abstract: | From the leaves of Aphananthe aspera (Thunb.) Planch. (Family: Cannabaceae), six flavonol glycosides, such as quercetin 3-O-β-glucopyranoside (1), kaempferol 3-O-β-glucopyranoside (2), quercetin 3-O-rutinoside (3), kaempferol 3-O-rutinoside (4), quercetin 3-O-neohesperidoside (5) and kaempferol 3-O-neohesperidoside (6) were isolated and identified. Structure elucidation of these compounds was performed on the basis of NMR spectral data. All these compounds were isolated for the first time from the genus Aphananthe. Chemotaxonomic significance and distribution of these flavonoid derivatives among the genera of Cannabaceae are explained in detail. |
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| Keywords: | Cannabaceae Mukunoki Flavonol glycoside |
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